Effect of dithiothreitol on mercuric chloride- and uranyl nitrate-induced acute renal failure in the rat.
نویسندگان
چکیده
منابع مشابه
Effect of Sodium Selenide on Renal Toxicity Induced By Mercuric Chloride in Rat
Background and Aims: Mercury, with its oxidative activity, causes damage to the antioxidant enzymes thus resulting in physiological disorders. Sodium selenide is an antioxidant that protects antioxidant enzymes. The aim of this study was to investigate the protective effect of sodium selenide on renal toxicity induced by mercuric chloride in rats. Materials and Methods: Animals were divided in...
متن کاملThe Mechanism of Acute Renal Failure after Uranyl Nitrate ROLAND
Portions of this work were presented at the Annual Meeting of The American Federation for Clinical Research, Atlantic City, N. J., 5 May 1974. Received for publication 21 June 1974 and in revised form 18 November 1974. dose UN (0.047±0.013) and high dose (0.024±0.003 nVs/g kidney wt/mm Hg). Therefore UN decreases GFR by two mechanisms: (a) tubular damage leading to back-diffusion of solutes and...
متن کاملthe effect of aqueous extract of garlic on formalin-induced pain in male rats
چکیده اثر عصاره آبی سیر بر درد ناشی از آزمون فرمالین در موش صحرایی نر به کوشش نرگس اسکندری روزبهانی زمینه و هدف: گیاه سیر از خانواده لیلیاسه و گونهallium sativum بومی آسیای میانه بوده و از دوران ،باستان تاکنون به خواص درمانی متفاوت آن مثل: کاهندگی قندخون، کلسترول خون، فشار خون، اثرات مفیدآن بر دستگاه قلبی عروقی و بیماریهای انعقادی خون، اثرات آنتی اکسیداتیو، درمان بیماریهای تنفسی وگوارشی، ا...
15 صفحه اولExperimental acute renal failure induced by uranyl nitrate in the dog.
The diminished glomerular filtration rate observed in previous studies of acute renal failure induced by uranyl nitrate has been ascribed to backflow of glomerular filtrate through necrotic tubular epithelium, since renal blood flow was essentially normal. Renal blood flow (xenon washout) and renal function were studied serially for 96 hours after the administration of uranyl nitrate (10 mg/kg,...
متن کاملMelatonin attenuates acute renal failure and oxidative stress induced by mercuric chloride in rats.
We evaluated the effect of melatonin (Mel), a potent scavenger of reactive oxygen species, in the course of HgCl(2)-induced acute renal failure. Rats received by gastric gavage 1 mg/kg of Mel (n = 21) or vehicle (n = 21), 30 min before the subcutaneous injection of HgCl(2) (2.5 mg/kg). Rats were killed at 24, 48, and 72 h, and plasma creatinine (S(cr)), renal histology, proliferative activity, ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Kidney International
سال: 1977
ISSN: 0085-2538
DOI: 10.1038/ki.1977.88